Dr René Frank
- Position
- Group Leader and University Academic Fellow
- Areas of expertise
- Cryo-electron tomography; Neuroscienc;, Alzheimer’s disease
- R.Frank@leeds.ac.uk
- Location
- 6.41d Garstang
- Faculty
- Biological Sciences
- School
- Biomedical Sciences
Introduction
My group is using novel mouse genetic and biochemical labelling methods in combination with cryo-electron microscopy to determine in situ molecular structures of the mammalian brain. We are particularly interested in synaptic mechanisms, memory, and Alzheimer’s disease.
Current major projects
- Structural basis of memory in the mammalian brain
- In situ structure of Alzheimer’s disease pathology
- Novel probes for cryogenic correlated light-electron tomography
- Trans-synaptic signalling mechanisms