Dr René Frank


My group is using novel mouse genetic and biochemical labelling methods in combination with cryo-electron microscopy to determine in situ molecular structures of the mammalian brain. We are particularly interested in synaptic mechanisms, memory, and Alzheimer’s disease.

Current major projects

  • Structural basis of memory in the mammalian brain
  • In situ structure of Alzheimer’s disease pathology
  • Novel probes for cryogenic correlated light-electron tomography
  • Trans-synaptic signalling mechanisms