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Dr René Frank

Position
Group Leader and University Academic Fellow
Areas of expertise
Cryo-electron tomography; Neuroscienc;, Alzheimer’s disease
Location
6.41d Garstang
Faculty
Biological Sciences
School
Biomedical Sciences

Introduction

My group is using novel mouse genetic and biochemical labelling methods in combination with cryo-electron microscopy to determine in situ molecular structures of the mammalian brain. We are particularly interested in synaptic mechanisms, memory, and Alzheimer’s disease.

Current major projects

  • Structural basis of memory in the mammalian brain
  • In situ structure of Alzheimer’s disease pathology
  • Novel probes for cryogenic correlated light-electron tomography
  • Trans-synaptic signalling mechanisms