Dr René Frank
My group is using novel mouse genetic and biochemical labelling methods in combination with cryo-electron microscopy to determine in situ molecular structures of the mammalian brain. We are particularly interested in synaptic mechanisms, memory, and Alzheimer’s disease.
Current major projects
- Structural basis of memory in the mammalian brain
- In situ structure of Alzheimer’s disease pathology
- Novel probes for cryogenic correlated light-electron tomography
- Trans-synaptic signalling mechanisms