The Astbury Centre
The Astbury Centre brings together researchers from across the University - largely from physics, the biological sciences and chemistry - to allow interdisciplinary approaches to be harnessed to understand the molecular basis of life. The Centre has outstanding expertise and research infrastructure in chemical biology, biophysics and all of the major techniques in structural molecular biology. Together, these approaches are combined with analyses of biological function with the ultimate aim of understanding the molecular basis of biological mechanisms in living cells.
Our members address major questions associated with biological mechanisms in areas as diverse as membrane proteins; protein folding and assembly; viruses; and motor proteins. The Astbury Centre hosts 4-year PhD programmes funded by the Wellcome Trust and BBSRC that equip students with the wide range of expertise that may be used to address fundamental biological questions.
Download the Astbury Annual Report 2021
Download the Astbury Brochure (produced in 2020)
Watch the Astbury Centre video
Visit the Astbury Twitter account for the latest news and announcements.
New insights into β2-microglobulin amyloid aggregation
The aggregation of β2-microglobulin (β2m) into amyloid fibrils is associated with human disease, but subtly different variants of β2m are associated with diseases with distinct pathologies. Astbury researchers at the University of Leeds have used cryoEM to determine the structures of fibrils formed from three different variants under identical conditions in vitro. The research, from...
Megan Wright promoted to Associate Professor
Congratulations to Megan who has recently been promoted to Associate Professor following the completion of her University Academic Fellowship.
Molecules could target cardio-metabolic diseases
A spin out company called CalTIC has been launched by the University of Leeds and its research partners in Germany - the Lead Discovery Centre, a specialist drug discovery laboratory in Dortmund; the Max Planck Society; and Heidelberg University - to commercially exploit the research. Research over the past two decades has culminated in a...