- Emeritus Professor
- Areas of expertise
- mass spectrometry; electrospray ionisation; ion mobility spectrometry; native/biomolecular mass spectrometry; tandem mass spectrometry; FPOP; HDX.
My research is focused on developing and applying mass spectrometric techniques and methodologies to the analysis of biomolecules. Our work uses electrospray ionisation (ESI) non-covalent mass spectrometry (MS) coupled with ion mobility spectrometry (IMS) and thus we are able to measure the molecular mass and size (i.e. cross-sectional area) of individual biomolecules from within highly heterogeneous mixtures in a single experiment. We study protein folding and aggregation and their relevance to protein-related diseases.