Exploiting a chink in the armour of bacteria

Scientists have identified a key process in the way bacteria protect themselves from attack – and it heralds a new strategy in the hunt for antibiotics. The researchers from the University of Leeds have pieced together how bacteria build their outer, defensive wall – in essence, the cell’s armour plating. The research team focused on Escherichia coli, a bacteria found in animal and human intestines. But the process they discovered is shared by many pathogenic gram-negative bacteria, a number of which are becoming resistant to antibiotics.

Read the full press release on the Faculty of Biological Sciences website

Read Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients on the Nature website