Research Highlights

The five-year project will lead to a better understanding of fundamental biochemical processes of gene regulation and will identify new research strategies for tackling cancer and other diseases. Julie Aspden, Associate Professor of RNA at Leeds and principal investigator, said: “The goal of this project is not only to understand how genes are expressed by…
Professor Lorna Dougan has been awarded the British Biophysical Society Elspeth Garman Prize for Public Engagement for her pioneering work in developing and delivering creative public engagement resources to diverse communities. The prize is awarded every two years and recognises excellence in biological physics engagement. Biophysics is a vibrant scientific field, with world leading activity…
For 30 years, scientists have been trying to understand how a biological molecule self-assembles into a rogue protein-like substance, which is thought to play a key role in type-2 diabetes. A team of scientists at the University of Leeds has, for the first time, been able to identify the step-by-step changes that take place in…
New research has identified a way of using nanoclusters to bolster waning antibiotics. Tiny particles of gold could be the new weapon in the fight against bacterial antibiotic resistance, according to research just published. Scientists have been investigating the use of gold nanoclusters – each made up of about 25 atoms of gold – to…
Scientists have developed an approach that could help in the design of a new generation of synthetic biomaterials made from proteins. The biomaterials could eventually have applications in joint repair or wound healing as well as other fields of healthcare and food production. But one of the fundamental challenges is to control and fine tune…
An international team of researchers has shed new light on the way viruses evolved highly effective ways of spreading disease. The scientists, involving a team from the universities of Leeds and York, believe understanding that key moment in the natural history of viruses may eventually help with the design of novel delivery mechanisms for gene…
Scientists at Leeds are part of an international collaboration that has designed a protein that self-assembles into an artificial pore. The protein sequence spontaneously transforms into a “transmembrane beta-barrel” – a tiny conduit or pore that embeds itself into a lipid membrane, mimicking its natural counterparts which are found in the walls of bacterial cells…
Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package up’ their genetic code, allowing them to infect cells. Once a cell is infected, a virus needs to spread its genetic material to other cells. This is a complex process involving the creation of what are…
University of Leeds research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumour using antibodies. Microbubbles are small manufactured spheres half the size of a red blood cell – and scientists believe they can be used to transport drugs to highly specific locations within the body. Professor…
A visualisation made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy. The protein, called myosin, is known as a molecular motor because of the way it interacts with other proteins and energy molecules to generate force and movement. It is…