Using targeted microbubbles to administer toxic cancer drugs

University of Leeds research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumour using antibodies.

Microbubbles are small manufactured spheres half the size of a red blood cell – and scientists believe they can be used to transport drugs to highly specific locations within the body.

Professor Stephen Evans, head of the Molecular and Nanoscale Physics Group at Leeds said: “The results of this study are exciting because we not only show the very precise and targeted way microbubbles can be guided to cancer sites but that the efficacy of drug delivery is substantially improved, opening the way to use highly toxic drugs to fight cancer, without the harmful side effects. Put simply: you get more bang for your buck.”

Read the full press release on the University of Leeds website.

Read “Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues” on the Theranostics website.