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Chemical Biology

Within the Astbury Centre, chemists are engaged in a broad range of interdisciplinary, collaborative research to address biological, chemical and medical problems. These include designing and making new drugs, developing small molecule tools to probe and understand the molecular mechanisms that underpin biological mechanisms, pioneering new approaches in synthetic biology and engineering new enzymes to use in synthetic chemistry.

We have superb facilities for Chemical Biology including integrated synthetic and biological laboratories, computing dedicated to ligand screening and design, compound screening capabilities, and suites of equipment dedicated to the high-throughput synthesis and characterisation of small molecules. We use these facilities, in conjunction with biophysical, structural and cellular approaches, to address a wide range of problems of direct relevance to society.