Results 111 to 120 of 122
Scientists at the University of Leeds will run the equivalent of password cracking software to find the chemical keys to defeating the Ebola virus. A team from the University’s schools of Chemistry and Molecular and Cellular Biology have secured a £200,000 grant from the Wellcome Trust to find drugs to cure the disease. Read the...
A new £3.4 million programme will develop new tools to understand which interactions between proteins in the human body are relevant to disease. Currently, only a handful of drugs in clinical use work by targeting protein-protein interactions. A new £3.4 million programme will develop new tools to understand which interactions between proteins in the human...
Scientists have developed an innovative way of using one of the biggest problems facing health services—antibiotic resistance—to develop drugs to combat some of the most intractable diseases. Read the full press release here Read An in vivo platform for identifying inhibitors of protein aggregation in Nature Chemical Biology
Understanding how a plant virus assembles could lay the groundwork for future use to carry drugs into the human body. The Nature Communications paper investigates vital steps to understanding how safe, plant-based virus-like particles could be created in the future. Read the full press release here Read Mechanisms of assembly and genome packaging in an RNA...
The first images of motor proteins in action are published in the journal Nature Communications today. These proteins are vital to complex life, forming the transport infrastructure that allows different parts of cells to specialise in particular functions. Until now, the way they move has never been directly observed. Researchers at the University of Leeds...
The first images of motor proteins in action are published in the journal Nature Communications. These proteins are vital to complex life, forming the transport infrastructure that allows different parts of cells to specialise in particular functions. Until now, the way they move has never been directly observed. Read full press release here Read Direct...
The University of Leeds is investing £17 million in a state-of-the-art laboratory for structural biology research. The new facility will provide the University’s internationally renowned Astbury Centre for Structural Molecular Biology with instruments for Electron Microscopy and Nuclear Magnetic Resonance that are competitive with the very best in the world. Professor Sheena Radford FRS, Director...
Researchers have cracked a code that governs infections by a major group of viruses including the common cold and polio. Until now, scientists had not noticed the code, which had been hidden in plain sight in the sequence of the ribonucleic acid (RNA) that makes up this type of viral genome. But a paper published...
Scientists have shown that gold nanotubes have many applications in fighting cancer: internal nanoprobes for high-resolution imaging; drug delivery vehicles; and agents for destroying cancer cells. Read the full press release here Read Engineering Gold Nanotubes with Controlled Length and Near‐Infrared Absorption for Theranostic Applications in Advanced Functioning Materials
New synthetic anti-cancer molecule that targets two key mechanisms in the spread of malignant tumours through the body. The synthetic molecule JK-31 blocks the signalling of a “growth factor” chemical that promotes the creation of networks of blood vessels to feed tumours, but intervenes directly in the growth of the cancer itself, inhibiting a protein...