Results 11 to 20 of 140
A previously overlooked type of circular DNA may help explain why some children with leukaemia relapse, according to landmark research from the University of Leeds published in Nature. The research builds on earlier work that linked leukaemia (a type of blood cancer) to excised signal circles (ESCs) - circular forms of DNA that are normally...
Research has revealed how a tick-borne virus manipulates human brain chemistry to survive, offering new hope for diagnosis and treatment. The study found that the tick-borne encephalitis virus (TBEV), a disease transmitted through tick bites or unpasteurised dairy products, alters key molecules in the brain to aid its survival. With symptoms similar to flu, TBEV...
Dr Alexander Garvin has been awarded £125,000 to improve Lung cancer detection, as part of a £7.6 million national investment in scientific leaders. In its largest-ever funding initiative for early-career researchers, the Academy of Medical Sciences is investing £7.6 million to tackle urgent health challenges from Alzheimer’s disease, cancer and obesity to addiction and climate...
Researchers from across Europe, led by the University of Leeds, have joined forces to improve the production of antibody and cell-based therapies. Many proteins are modified by the addition of sugars, known as glycans, which have profound effects on their function, but often, a complex mixture of different glycans is found on proteins and cells....
Congratulations to Caffinity Biotech, a team of early-career researchers from the Astbury Centre, on winning "Best disruptive food and drink business plan" sponsored by the Food Consortium Collaborative Training Partnership (CTP) at the YES24 competition. Your Entrepreneurs Scheme (YES) is a competition that challenges participants to develop innovative solutions to address pressing global challenges. Celebrating its...
Scientists and clinicians at the University of Leeds exploring new radiotherapy treatments and technologies have been given a major cash boost from Cancer Research UK (CRUK). Over the next five years the CRUK Leeds Radiation Research Centre of Excellence (RadNet Leeds) will receive £2.94 million from the charity. Combined with a further £5.6 million leveraged funding from...
A study, led by University of Leeds and University of Oxford, has revealed new knowledge about an enzyme involved in cancer treatment. The enzyme, called Aurora-A, is currently used as drug target for some lung cancers because it plays an important role in controlling cell division. These current cancer treatments work by blocking Aurora-A completely...
Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more accurately than ever before, according to a new study co-led by Leeds. They hope their findings could eventually lead to simple, at-home tests for diseases such as cholera, which can kill within hours, and...
For the first time, academics in the Astbury Centre have recorded the highest mass-to-charge ratios ever measured on an Orbitrap machine. But how did they do it? A recently developed technique, called electron capture charge reduction, reduces charge in biomolecular structures. It’s now offering huge promise for analysing larger sized proteins – a current limitation...
University of Leeds has received a grant of £1.1million to enable world leading research into disease. The grant, which has been awarded by the Wolfson Foundation, will be used to fund high-resolution microscopes which use fluorescent dyes to see into cells in exquisite detail. This new equipment will enable scientists to understand the structure of...