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Leeds scientist wins £125k funding to develop new protein-level strategies for fighting lung cancer.

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Dr Alexander Garvin has been awarded £125,000 to improve Lung cancer detection, as part of a £7.6 million national investment in scientific leaders. In its largest-ever funding initiative for early-career researchers, the Academy of Medical Sciences is investing £7.6 million to tackle urgent health challenges from Alzheimer’s disease, cancer and obesity to addiction and climate...

Leeds-led consortium secures €3m to pioneer next-generation antibody and cell therapies

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Researchers from across Europe, led by the University of Leeds, have joined forces to improve the production of antibody and cell-based therapies. Many proteins are modified by the addition of sugars, known as glycans, which have profound effects on their function, but often, a complex mixture of different glycans is found on proteins and cells....

Winners of Best disruptive food and drink business plan at the YES24 competition

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Congratulations to Caffinity Biotech, a team of early-career researchers from the Astbury Centre, on winning "Best disruptive food and drink business plan" sponsored by the Food Consortium Collaborative Training Partnership (CTP) at the YES24 competition. Your Entrepreneurs Scheme (YES) is a competition that challenges participants to develop innovative solutions to address pressing global challenges. Celebrating its...

Major funding boost for radiotherapy research

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Scientists and clinicians at the University of Leeds exploring new radiotherapy treatments and technologies have been given a major cash boost from Cancer Research UK (CRUK). Over the next five years the CRUK Leeds Radiation Research Centre of Excellence (RadNet Leeds) will receive £2.94 million from the charity. Combined with a further £5.6 million leveraged funding from...

Researchers discover new insights into a key protein in cell division and cancer

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A study, led by University of Leeds and University of Oxford, has revealed new knowledge about an enzyme involved in cancer treatment. The enzyme, called Aurora-A, is currently used as drug target for some lung cancers because it plays an important role in controlling cell division. These current cancer treatments work by blocking Aurora-A completely...

New Mass Spectrometry Frontiers

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For the first time, academics in the Astbury Centre have recorded the highest mass-to-charge ratios ever measured on an Orbitrap machine. But how did they do it? A recently developed technique, called electron capture charge reduction, reduces charge in biomolecular structures. It’s now offering huge promise for analysing larger sized proteins – a current limitation...

Pioneering disease research gets major investment boost

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University of Leeds has received a grant of £1.1million to enable world leading research into disease. The grant, which has been awarded by the Wolfson Foundation, will be used to fund high-resolution microscopes which use fluorescent dyes to see into cells in exquisite detail. This new equipment will enable scientists to understand the structure of...

Unlocking the power of nanopores

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Scientists take one step closer to uncovering new sensing technology. Scientists at University of Leeds are part of an international collaboration that has described a new approach to designing proteins from scratch. The approach uses Transmembrane β-barrel pores (TMBs), nanosized proteins which are extensively used for single-molecule DNA and RNA sequencing –an analysis method that...

Seeing inside Alzheimer’s disease brain

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Scientists investigating Alzheimer’s disease have determined the structure of molecules within a human brain for the very first time. The study describes how scientists used cryo-electron tomography, guided by fluorescence microscopy, to explore deep inside an Alzheimer’s disease donor brain. This gave 3-dimensional maps in which they could observe proteins, the molecular building blocks of...