Results 21 to 30 of 123
The aggregation of β2-microglobulin (β2m) into amyloid fibrils is associated with human disease, but subtly different variants of β2m are associated with diseases with distinct pathologies. Astbury researchers at the University of Leeds have used cryoEM to determine the structures of fibrils formed from three different variants under identical conditions in vitro. The research, from...
Congratulations to Megan who has recently been promoted to Associate Professor following the completion of her University Academic Fellowship.
A spin out company called CalTIC has been launched by the University of Leeds and its research partners in Germany - the Lead Discovery Centre, a specialist drug discovery laboratory in Dortmund; the Max Planck Society; and Heidelberg University - to commercially exploit the research. Research over the past two decades has culminated in a...
The five-year project will lead to a better understanding of fundamental biochemical processes of gene regulation and will identify new research strategies for tackling cancer and other diseases. Julie Aspden, Associate Professor of RNA at Leeds and principal investigator, said: “The goal of this project is not only to understand how genes are expressed by...
Fran Chandler (Zeqiraj lab) was invited to give a talk at the first mass photometry users meeting at the Kavli Institute in Oxford where she won a prize for best talk. Congratulations Fran!
Professor Lorna Dougan has been awarded the British Biophysical Society Elspeth Garman Prize for Public Engagement for her pioneering work in developing and delivering creative public engagement resources to diverse communities. The prize is awarded every two years and recognises excellence in biological physics engagement. Biophysics is a vibrant scientific field, with world leading activity...
Richard Henderson – a molecular biologist and biophysicist - was jointly awarded the Nobel Prize in 2017 for developing cryo-electron microscopy techniques to determine in high resolution the structure of important biomolecules. He delivered the keynote speech at the Astbury Conversation 2022. Professor Simone Buitendijk, Vice-Chancellor of the University of Leeds, said: “It is a...
The Astbury Centre joins scientists across the world in watching events in Ukraine with horror. We’ve joined the EMBO #SolidarityList, and stand in solidarity with Ukraine and life scientists working there. We would be happy to support displaced Ukrainian scientists at any level, including hosting, in any way we can. If you think we can...
For 30 years, scientists have been trying to understand how a biological molecule self-assembles into a rogue protein-like substance, which is thought to play a key role in type-2 diabetes. A team of scientists at the University of Leeds has, for the first time, been able to identify the step-by-step changes that take place in...
For 30 years, scientists have been trying to understand how a biological molecule self-assembles into a rogue protein-like substance, which is thought to play a key role in type-2 diabetes. A team of scientists at the University of Leeds has, for the first time, been able to identify the step-by-step changes that take place in...