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Exploiting a chink in the armour of bacteria

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Scientists have identified a key process in the way bacteria protect themselves from attack - and it heralds a new strategy in the hunt for antibiotics. The researchers from the University of Leeds have pieced together how bacteria build their outer, defensive wall - in essence, the cell’s armour plating. The research team focused on...

Covid19 research at the Astbury Biostructure Laboratory electron microscope facility

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The BBC recently featured our research facilities on Look North. Read more about the Covid19 research currently ongoing at the Astbury Biostructure Laboratory electron microscope facility. The Astbury Biostructure Laboratory Electron Microscopy Facility is currently offering access to state-of-the-art cryo-electron microscopes for COVID-19 research. A research group from the University of York is taking advantage...

‘Directing’ evolution to identify potential drugs

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Scientists have developed a technique that could significantly reduce the time to discover potential new antibody-based drugs to treat disease. Read the full press release on the University of Leeds website Read An in vivo platform to select and evolve aggregation-resistant proteins on the Nature Comms website

Nature's lethal shape-shifter

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Every picture tells a story… none more so than this detailed visualisation of a strain of the norovirus. Created from 13,000 separate images taken by an electron microscope, it reveals in rich detail the structure of the virus. It shows bump-like protrusions on the outside of the virus capsid, the protein shell that holds the...

Scientists identify new target for Parkinson’s therapies

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A master control region of a protein linked to Parkinson’s disease has been identified for the first time. The finding, made by scientists from the University of Leeds’ Astbury Centre for Structural Molecular Biology, provides a new target for the development of therapies to try and slow down or even prevent the disease. Parkinson’s affects...

High-performance computing to aid scientific discovery

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The University is to be part of two supercomputing centres - to boost the ability of researchers to make major scientific breakthroughs. The announcement is part of a £27 million investment from the Engineering and Physical Sciences Research Council to ensure academics have access to state-of-the-art, high-performance computing facilities. Dr Sarah Harris, Associate Professor in...

Dr Ste Muench promoted to Associate Professor

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Congratulations to Ste Muench (pictured centre) who has been promoted to Associate Professor. Ste is a member of the School of Biomedical Sciences and the Astbury Centre.

Leeds research could revolutionise vaccine development

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Research which has identified a way of making a safer and cheaper polio vaccine is to be scaled-up – to see if it could be used in commercial vaccine production. The new approach, which has the potential to revolutionise vaccine development across the board, is the result of a scientific collaboration led by the University....