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Finding a safer way to make the Polio vaccine

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Researchers at the University of Leeds are developing a cheaper and safer way of making the polio vaccine. The pioneering work is featured in the latest MadeAtUni campaign, a celebration of the pioneering research taking place in UK universities. The focus of the campaign is scientists involved in health research and innovation. Read the full...

Tackling viral diseases

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As part of the University of Leeds' Global Challenge research, visiting researcher Dr Adeyemi works alongside Professor Nicola Stonehouse to tackle global problems. Funding from the UK’s Global Challenges Research Fund has allowed molecular biologist Dr Oluwapelumi Adeyemito to be appointed a research visitor at the University of Leeds. Read the full press release on...

Filming how our immune system kills bacteria

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The research, published in Nature Communications, provides us with a better understanding of how the immune system kills bacteria and why our own cells remain intact. This may guide the development of new therapies that harness the immune system against bacterial infections, and strategies that repurpose the immune system to act against other rogue cells...

Leeds scientists attempt to tackle HIV-related cancer

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Scientists are attempting to tackle a virus that causes Kaposi’s sarcoma, a skin cancer that is common amongst those with HIV. Kaposi’s sarcoma is caused by the virus Kaposi’s sarcoma-associated herpesvirus (KSHV). It predominantly affects people between the ages of 20 and 49. A new international research consortia from the University of Leeds, alongside Rhodes...

Key step forward in tackling neurodegenerative diseases

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A protein complex has been shown to play a key role in preventing the build-up of toxic plaques in the brain linked to neurodegenerative disorders such as Alzheimer’s and Huntington’s disease. Read Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies on the Molecular Cell website

Key step forward in tackling neurodegenerative diseases

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A protein complex has been shown to play a key role in preventing the build-up of toxic plaques in the brain linked to neurodegenerative disorders such as Alzheimer’s and Huntington’s disease. An international team of researchers from the Universities of Leeds, Stanford (USA) and Konstanz (Germany) have discovered that the nascent polypeptide-associated complex (NAC) helps...

Cycling scientists cross the country on charity microscope tour

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A team of cycling scientists from the Astbury Biostructure Laboratory at the University of Leeds are pedalling across the UK later this month, to raise money for the human rights charity, the International Justice Mission. During their week-long, 660 mile tour they will be visiting every cryo-electron microscope in the country. The powerful microscopes stand...

Understanding how peptides self-assemble

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Scientists have developed an integrated computational and experimental approach to investigate the way proteins and peptides – chains of amino acids – aggregate. The study describes research focussed on co-aggregation of two peptide fragments of the Amyloid-Beta (Ab) peptide implicated in Alzheimer’s disease as a model system.

Ten-foot tall microscopes helping combat world’s worst diseases

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The century-long mission to understand how the proteins which underpin amyloid-based diseases like Alzheimer’s, Huntington’s and Parkinson’s has taken major steps forward in the last 12 months. High-powered microscopes using electrons instead of light to ‘see’ the actual shape of samples put under them, at near atomic-levels of detail, have only recently become available to...

Devastating plant virus revealed in atomic detail

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The complex 3D structure of one of the world’s most lethal families of plant viruses has been revealed in unprecedented detail by scientists at the University of Leeds. Geminiviruses are responsible for diseases affecting crops such as cassava and maize in Africa, cotton in the Indian subcontinent and tomatoes across Europe. Being able to see...