2020 BBS Kendrew Doctoral Thesis Prize Winner
Congratulations to Leeds and Astbury Centre alumnus Dan Hurdiss for being awarded the 2020 BBS Kendrew Doctoral Thesis Prize. Dan will give a prize lecture at the BBS Symposium. Well done Dan!
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The intricate protein architecture linked to disease
Scientists have for the first time identified the structure of a protein fibre linked to early-onset type 2 diabetes. In research published in the journal Nature Structural and Molecular Biology, scientists at the University of Leeds report that they have been able to visualise the structure of amylin fibrils using the latest electron microscope technology....
Advanced imaging shows real-time molecular interaction
Visualising how molecules move in cells or interact with drugs will be possible with one of the world’s most advanced imaging centres being developed at the University. Known as the Wolfson Imaging Facility, it will enable scientists to watch viruses attacking cells, immune cells getting ready to attack their targets and the cellular “railroads” used to transport molecules to their correct destinations....
Dr Peter Adams promoted to Associate Professor
Congratulations to Peter Adams who has been promoted to Associate Professor following the completion of his University Academic Fellowship.
Emeritus Professor Alison Ashcroft awarded Thomson Medal for 2020 by the International Mass Spectrometry Foundation
Alison Ashcroft, Emeritus Professor of Biomolecular Mass Spectrometry, has been awarded the prestigious Thomson Medal for 2020 by the International Mass Spectrometry Foundation (IMSF). The award is for “both outstanding achievements in mass spectrometry and distinguished services to international mass spectrometry societies".
Exploiting a chink in the armour of bacteria
Scientists have identified a key process in the way bacteria protect themselves from attack - and it heralds a new strategy in the hunt for antibiotics. The researchers from the University of Leeds have pieced together how bacteria build their outer, defensive wall - in essence, the cell’s armour plating. The research team focused on...
Covid19 research at the Astbury Biostructure Laboratory electron microscope facility
The BBC recently featured our research facilities on Look North. Read more about the Covid19 research currently ongoing at the Astbury Biostructure Laboratory electron microscope facility. The Astbury Biostructure Laboratory Electron Microscopy Facility is currently offering access to state-of-the-art cryo-electron microscopes for COVID-19 research. A research group from the University of York is taking advantage...
‘Directing’ evolution to identify potential drugs
Scientists have developed a technique that could significantly reduce the time to discover potential new antibody-based drugs to treat disease. Read the full press release on the University of Leeds website Read An in vivo platform to select and evolve aggregation-resistant proteins on the Nature Comms website
Nature's lethal shape-shifter
Every picture tells a story… none more so than this detailed visualisation of a strain of the norovirus. Created from 13,000 separate images taken by an electron microscope, it reveals in rich detail the structure of the virus. It shows bump-like protrusions on the outside of the virus capsid, the protein shell that holds the...
Scientists identify new target for Parkinson’s therapies
A master control region of a protein linked to Parkinson’s disease has been identified for the first time. The finding, made by scientists from the University of Leeds’ Astbury Centre for Structural Molecular Biology, provides a new target for the development of therapies to try and slow down or even prevent the disease. Parkinson’s affects...