Results 31 to 40 of 110
A visualisation made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy. The protein, called myosin, is known as a molecular motor because of the way it interacts with other proteins and energy molecules to generate force and movement. It is...
Scientists have discovered how drug-like small molecules can regulate the activity of therapeutically relevant ion channels - and their findings could transform ongoing drug development efforts. The new study provides detailed insight into the regulation of TRPC5 ion channels, which allow positively charged ions such as calcium, sodium and potassium to flow in and out...
Congratulations to David Brockwell on his recent promotion to Professor.
Congratulations to Andrew Macdonald who has been promoted to Professor of Tumour Virology. Andrew is Head of School for Molecular and Cellular Biology and a member of the Astbury Centre.
Researchers at the University of Leeds and University of Cambridge demonstrated that tiny gold nanotubes could treat cancer caused by asbestos fibres. In the study, the scientists showed that – when inside cancer cells – the nanotubes can absorb light, which causes them to heat up and kill the cells. The new research may pave...
Professor Sheena Radford, the Director of the Astbury Centre for Structural Molecular Biology, has been honoured with an OBE, for her research at the frontiers of molecular biology. As director of the Astbury Centre for Structural Molecular Biology, Professor Sheena Radford has led a large group of researchers investigating the complex molecular basis of life....
The University of Leeds has secured a £5.4 million grant to identify new techniques for investigating and manipulating the chemical building blocks of life - proteins. The five-year project - in collaboration with the University of Oxford - will lead to a better understanding of fundamental biochemical processes and will identify new research strategies for...
Congratulations to Leeds and Astbury Centre alumnus Dan Hurdiss for being awarded the 2020 BBS Kendrew Doctoral Thesis Prize. Dan will give a prize lecture at the BBS Symposium. Well done Dan!
Scientists have for the first time identified the structure of a protein fibre linked to early-onset type 2 diabetes. In research published in the journal Nature Structural and Molecular Biology, scientists at the University of Leeds report that they have been able to visualise the structure of amylin fibrils using the latest electron microscope technology....
Visualising how molecules move in cells or interact with drugs will be possible with one of the world’s most advanced imaging centres being developed at the University. Known as the Wolfson Imaging Facility, it will enable scientists to watch viruses attacking cells, immune cells getting ready to attack their targets and the cellular “railroads” used to transport molecules to their correct destinations....