Circular Dichroism Spectroscopy

Application

What can CD do for you?

Determination of protein secondary structure
Determination of optical purity
Analysis of the tertiary structure of proteins and conformational changes
Comparison of the secondary and tertiary structures of wild-type and mutant proteins
Binding studies involving conformational changes
Nucleic acid structure and changes upon binding or melting
Thermodynamic parameters from temperature dependencies of CD signals
Kinetics of conformational changes on msec timescales

Equipment

Chirascan Plus (Applied Photophysics)

Location

Astbury 10.118

Contact

Nasir Khan
School of Molecular & Cellular Biology
Email: g.n.khan@leeds.ac.uk
Tel: 0113 343 3014

Further information

https://biologicalsciences.leeds.ac.uk/facilities/doc/circular-dichroism